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Friday, 20 September 2019

India’s Youngest Successful Liver Transplantation on a One-Month-Old Baby, Performed at Dr Rela Institute & Medical Centre

 03:05     Dr Rela, Dr. Rela Institute, Liver Transplant, Liver Transplantation, One-Month-Old Baby, Prof Mohamed Rela, Successful Liver Transplant     2 comments   


Dr. Rela Institute & Medical Centre performed India’s first successful liver transplantation on a one-month-old baby on 23rd July in the city. The youngest child to undergo liver transplantation in the country is now doing well and is under the hospital’s postoperative care.
This rare surgery was performed on Aadav (name changed) from Mumbai, who had developed vomiting in the first week of birth, requiring immediate hospitalization. What was believed to be a simple infection, was later diagnosed as urea cycle disorder, which is a metabolic disorder.
When the parents realized that liver transplantation was the only curative treatment option, they shifted the child from Mumbai to Dr. Rela Institute & Medical Centre. The 10-hour long surgery was performed by an expert team of pediatric transplant surgeons and pediatric anesthetists.
Commenting on the first of its kind surgery, Prof Mohamed Rela, Chairman and Managing Director of Dr Rela Institute & Medical Centre, said, “I am glad that a quick diagnosis and timely supportive measures were initiated in mumbai that has prevented the child from having brain damage. The parents took the right decision to let their baby undergo liver transplantation. No centre in India has so far performed liver transplantation on such a young infant.
He added that though metabolic disorders are rare, they are important causes of liver diseases and liver failures in newborns. However, liver transplantation can save them effectively. Though technically difficult neither the weight, nor the age of the baby is a limiting factor.
Talking about the disorder, Dr Naresh Shanmugam, Paediatric Hepatologist and Director for Women & Child Health Department at Dr Rela Institute & Medical Centre, said, “Urea cycle disorder results in high ammonia levels in the blood. The condition refers to the inability of the liver to convert ammonia, which is produced as a byproduct while the body metabolis es proteins, into urea. As the presence of ammonia in the blood increases, it causes swelling in the brain resulting in coma and even death. Immediate action includes stopping protein intake and do dialysis to remove the ammonia. But liver transplantation is the permanent solution.
He added that on average one in 3000 children are born with some form of metabolic disorders in the world. The metabolic disorders can be effectively detected by what is known as the heel prick test, which requires only one drop of blood.
Dr. Ilankumaran Kaliamoorthy, Chairman, Medical Advisory Board at Dr Rela Institute & Medical Centre, said, “Performing liver transplantation in newborn & underweight babies is very challenging. At Dr. Rela Institute, we believe that with our expertise, world-class facilities & infrastructure, age is no barrier for liver transplantation. We have emerged as the largest liver transplant unit performing liver transplantation for a wide age range from newborns to over 70 years old.
Dr. Rela Institute & Medical Centre have the expertise and well-equipped paediatric and newborn intensive care unit to perform complex liver, bone marrow, kidney and intestinal transplant surgeries on babies successfully.

About Dr. Rela Institute & Medical Centre:

Dr. Rela Institute & Medical Centre (RIMC), an International Medical facility, is a quaternary care hospital dedicated to fostering and responding to the needs of a diverse patient population. The hospital provides high quality healthcare with state-of the art infrastructure facilities and experienced, caring medical professionals.
RIMC is designed to provide multi-speciality care with special focus on multi-organ transplantation and critically ill patients. In addition to quaternary care in all specialties, the hospital is committed to providing day-to- day “primary and secondary care” to patients. RIMC has one of the world’s largest dedicated liver intensive care units.
RIMC is a multi-super specialty hospital in a sprawling landscape of 36 acres located in Chromepet, Chennai, Tamilnadu, India.
  • The facility, with 450 beds inclusive of 130 critical-care beds, 14 operating rooms and sophisticated reference laboratories and radiology services, is conveniently located close to road, rail and air transport.
  • RIMC is led and managed by world-renowned doctors who are committed to healthcare.
  • RIMC offers a wide spectrum of clinical care, education and research.
  • RIMC is driven by patient needs, comfort and trust.
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24-Year old Mumbai student undergoes Heart and Lung Transplant at Global Hospital to conquer a rare and complex Congenital Heart Disease

 02:57     congenital heart disease, Dr Sandeep Attawar, Global Hospital, Global Hospital Mumbai, Heart Transplant, Lung Transplant, Mumbai student, young girl mumbai     1 comment   

Mumbai : A 24 year old Mumbai girl who was suffering from a rare and complex congenital heart disease underwent a combined heart and lung transplant at Global Hospital, Mumbai. Akshara a resident of Panvel, Mumbai suffered from ventricular septal defect since childhood and this defect over the years led to Eisenmenger’s syndrome. Although she was managed medically for a very long time, her condition worsened off late, and she had to be put on home-based oxygen therapy. The 24-year-old underwent a combined heart and lung transplant in the month of June 2019 and is recovering well.


The burden of patients with inoperable adult congenital heart disease and secondary pulmonary hypertension in this country is overwhelming. These individuals have a condition called Eisenmengers syndrome. Many of them continue to turn deeply blue over time and develop secondary complications like cerebral strokes, severe right heart failure, infective endocarditis and die painful deaths after suffering immeasurably.
Dr Sandeep Attawar, Director and Chair of the Heart & Lung Program, Gleneagles Global Hospitals said,“The individuals who have Eisenmengers syndrome could have undergone corrective heart surgery in their infancy or childhood that would have prevented this fate. However, it is only of recent that these facilities have been more common place in this country. So, these individuals that missed the bus, now are condemned to a pathetic existence unless an option such as the replacement of these seriously damaged organs is considered or feasible.”
“However, for the replacement of the seriously damaged organs, there has to be an increase in deceased organ donation,” stated Dr Sandeep.
He also mentioned that there is an uptick in awareness on organ donation and a ray of hope for individuals with this advanced and medically untreatable heart disease.
“The final solution for Eisenmengers syndrome is a heart and double lung transplantation. Akshara is one such young girl who had ventricular septal defect that wasn’t operated upon in her childhood. Heart-lung transplantation is the simultaneous surgical replacement of the heart and lungs in patients having end-stage cardiac and pulmonary disease. It is a viable treatment option,” mentioned Dr Attawar.
Patients who are chosen for the heart and lung transplantation are selected carefully after a series of coordinated and properly sequenced steps. As per  The International Society for Heart and Lung Transplantation, the indications for heart and lung transplant are congenital heart disease with Eisenmenger syndrome followed by idiopathic primary pulmonary hypertension with terminal right heart failure and cystic fibrosis with severe right heart dysfunction.
Akshara’s transplant lasted for 6 –7 hours. Post-surgery she was rehabilitated and was subsequently discharged in mid-July. She has been regularly following up with the clinical team and is recuperating well. Her follow up lung biopsies and levels of immunosuppressive medications are being monitored closely and treated under close medical supervision.
Patient Akshara Aher says,  ” I am thankful to Global Hospital transplant team who have helped me to pursue my dream as a pharmacist & follow her hobby to dance and mountain climbing in her second phase of life.
Dr Vivek Talaulikar, Chief Executive Officer, Global Hospital said, “I would like to thank our doctor teams for their tremendous efforts that they have put in to give Akshara a new lease of life. Till date, Global Hospital, Mumbai, has successfully carried out three bilateral lung transplants, and 1 combined heart and bilateral lung transplant. Our program will offer a safe and caring atmosphere for all patients like all our other organ transplant programs running for decades across India.”
“I would specially thank the donor family who have taken up a brave cause of donating the organs of their loved ones. Today as you see, organ donation has given a new life for this youngster. I would appeal to the communities via the media to come forward and pledge for organ donation,” added Dr Vivek.
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