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Thursday, 28 February 2019

Robotic surgery beneficial for urology patients [Sponsored content]

 00:02     advance urology robotic surgery, robotic surgery for urology, robotic urology surgery, urology robotic patient, urology robotic surgery     No comments   

Robotic surgery beneficial for urology patients
source - www.newbernsj.com
Urology-related robotic surgery is a huge benefit to patients who previously would have had to undergo open surgery with its long incisions and long hospital stays, said Dr. Hoyt B. Doak IV of CarolinaEast Urology in New Bern.
“For us that’s a really big deal, to be able to avoid a big open incision,” said Doak, who has been doing robotic surgeries for seven years, with five of those years at CarolinaEast Medical Center.
While surgeons in other specialties could be doing some surgeries robotically, laparoscopically or open, those in urology essentially have only two choices – robotic or open, he said.
“The cases that we do in urology are cases that are mostly just too technically difficult to be done laparoscopically,” Doak said. “They require sewing and fairly complex reconstruction that requires suturing. It is very difficult laparoscopically unless you’re a highly experienced laparoscopic surgeon that doesn’t really do anything else.”
In urology robotic surgery is compared to open surgery for most cases and certainly for the robotic prostatectomy and partial nephrectomy – surgeries for cancer of the prostate and kidney, he said.
The prostatectomy involves removing the prostate, a walnut-sized organ that sits in the very bottom of the pelvis.
“It’s a really very tight space,” Doak said.
If the prostatectomy is done with open surgery, it requires a 4- to 5-inch incision.

About prostate cancer
Other than skin cancer, prostate cancer is the most common cancer in American men. The American Cancer Society’s estimates for prostate cancer in the United States for 2019 are:
• About 174,650 new cases of prostate cancer.
• About 31,620 deaths from prostate cancer.
Risk of prostate cancer
About 1 man in 9 will be diagnosed with prostate cancer during his lifetime.
Prostate cancer develops mainly in older men and in African-American men. About 6 cases in 10 are diagnosed in men age 65 or older, and it is rare before age 40. The average age at the time of diagnosis is about 66.
Deaths from prostate cancer
Prostate cancer is the second leading cause of cancer death in American men, behind lung cancer. About 1 man in 41 will die of prostate cancer.
Prostate cancer can be a serious disease, but most men diagnosed with prostate cancer do not die from it. In fact, more than 2.9 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.
Source: American Cancer Society
“Visibility down in that space when you’re doing an open prostatectomy is very poor,” he said. “A lot of the surgery has to be done by feel just because you can’t see down there because there’s too much stuff in the way.”
When a prostatectomy is done robotically, a camera is put in through a tiny incision at the belly button, with instruments inserted in similar incisions on either side.
“We can take that camera all the way deep down in the pelvis and see exactly what’s going on down there,” Doak said. “Visibility is excellent. We can see right where the nerves and the blood vessels are that are responsible for potency, for sexual function. We can see the urethra and the bladder. It allows for really good visualization of what’s going on.”
From the patient’s standpoint, he said, the recovery is shorter, the pain is less, the blood loss is less and there is a lower stricture rate.
“In terms of other things that patients care about like erectile dysfunction, urinary continence and that kind of thing, the robot has never been proven to be superior to open surgery,” Doak said.
But a robotic prostatectomy does offer the benefits of minimally invasive surgery.
“Our patients go home the next day instead of spending two or three nights in the hospital and they require very little pain medicine,” he said. “Many of my patients will go home and not require any narcotic pain medicine. They’ll just go home on Tylenol or ibuprofen. I don’t send them home without narcotic pain medicine, but a lot of times they will come back and tell me they didn’t need it at all, or they only took two pills.”
For the kidney cancer surgeries such as the partial nephrectomy, the open alternative is extremely morbid, requiring a large, painful incision, Doak said.
“Those patients used to stay in the hospital for a long time – three, four or five days,” he said. “They used to have to have an epidural for pain control for several days and would get tons of narcotics for pain. It was a really tough surgery to have.”
The benefit of the partial nephrectomy is that it allows the surgeon to remove the part of the kidney that has cancer and leave the rest of the kidney in place.
“A robotic partial nephrectomy allows us to do that with much less morbidity than we used to have to inflict on people,” Doak said. “They have great outcomes. They are able to retain their kidney and they are able to go home sometimes the next day or sometimes after two nights. They are up on their feet, usually, the same night as surgery. It is like night and day from having a big open surgery.”
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Wednesday, 27 February 2019

New Stem Cell Therapy Can Treat Rare Blood Disorders

 23:34     Blood Disorders, Stem Cell Therapy, stem cell therapy treat blood cancer, stem cell treatment Blood Disorders, Treat Rare Blood Disorders     No comments   

New Stem Cell Therapy Can Treat Rare Blood Disorders
SOURCE - valuewalk.com

It’s extremely difficult to treat rare health disorders which can be fatal. However a new, private biotech project aims to change that, after combining CRISPR, a gene-editing tool which is bacteria-derived, and stem cell therapy. Now, this new stem cell therapy will treat the first human patient suffering from a rare blood disorder.
Vertex Pharmaceuticals and CRISPR Therapeutics announced that they are treating a patient who suffers from beta thalassemia, using the new stem cell therapy. The therapy is using CRISPR/Cas9 hematopoietic stem cell therapy, also called CTX001.
According to the press release, the new technique is still in clinical research, but it’s ready enough to treat human patients, yielding good results so far. Using this approach, researchers also want to learn whether they’ll be able to use the same approach to cure sickle cell disease. The clinical study with a human patient will be conducted in the U.S. in mid-2019.
“We have made tremendous progress with CTX001 and are pleased to announce that we’ve treated the first patient with beta thalassemia in this clinical study,” Dr Samarth Kulkarni, Chief Executive Officer of CRISPR Therapeutics, said in the press release. “Treating the first patient in this study marks an important scientific and medical milestone and the beginning of our efforts to fully realize the promise of CRISPR/Cas9 therapies as a new class of potentially transformative medicines to treat serious diseases.”
Scientists need to learn more about the rare blood disorders to be able to treat them efficiently. Beta thalassemia is a blood disorder which is inherited through genetics. People who suffer from this disorder are not able to form enough hemoglobin in their body, which is a protein inside red blood cells and is used for carrying oxygen through the body in the breathing process. Lack of hemoglobin is responsible for many conditions like anemia, shortage of breath and fatigue.
The new stem cell therapy would see researchers take a patient’s hematopoietic stem cells through blood samples and change them by using the CRISPR/Cas9 technology. This would make higher levels of fetal hemoglobin to be produced in the red blood cells.
Fetal hemoglobin is a special kind of hemoglobin which is present in the human body when we are born. However, as a person grows up, it is replaced by an adult form of hemoglobin.
The treated blood cells would then be reinfused back into the bloodstream, with the ability to produce fetal hemoglobin which would hold more oxygen.
“Beta thalassemia and sickle cell disease are serious, life-threatening diseases, and we are evaluating ex vivo treatment with CTX001 with the goal of creating a one-time potential curative therapy,” added Dr David Altshuler, Executive Vice President and Chief Scientific Officer at Vertex. “Our collaboration with CRISPR Therapeutics offers an exciting new potential therapeutic approach that complements our strategy of using scientific innovation to create transformative medicines for serious diseases.”
According to the report in Bloomberg, the new therapy has sparked curiosity and attention in the media since Monday, when it was announced, as well as many other biotech companies working in the same field.
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Wednesday, 13 February 2019

Football: Napoli blow as Spanish defender Albiol undergoes knee surgery

 23:19     Albiol knee surgery, Albiol knee surgrey in london, Albiol undergoes knee surgery, knee surgery, knee surgery Albiol, Raul Albiol knee surgery     No comments   

Football: Napoli blow as Spanish defender Albiol undergoes knee surgery
source: www.channelnewsasia.com

MILAN: Napoli's Spanish international defender Raul Albiol has undergone knee surgery in London, the Serie A club said on Tuesday.

"Raul Albiol underwent surgery to clean the patellar tendon of the left knee this morning at the Princess Grace Hospital in London," the club said in a statement.

"The surgery was perfectly successful. In the coming days, the recovery time will be assessed."
Albiol - winner of the 2010 World Cup and two European Championship titles with Spain - could be sidelined for at least a month, according to reports.

The absence of the charismatic 33-year-old who suffers from tendinopathy to the knee is a blow for Napoli who are second in the Italian league this season - 11 points behind champions Juventus.

The club also begins their Europa League campaign against FC Zurich on Thursday, after dropping out of the Champions League.

Albiol joined Napoli in 2013 from Real Madrid where he won La Liga in 2012.

He also won the UEFA Cup trophy with previous club Valencia in 2004.

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Cody Undergoes Arthroscopic Knee Surgery

 23:06     Arthroscopic Knee Surgery, arthroscopic knee surgery recovery, Arthroscopy surgery, cody Arthroscopic Knee Surgery, Cody knee surgery     No comments   

Cody Undergoes Arthroscopic Knee Surgery
source:www.f4wonline.com
After suffering the injury back in November, Cody Rhodes underwent surgery on his knee this morning.
Cody tweeted after having surgery: "Surgery completed. Went smooth. Back to work. (Cowabunga I guess)"
Brandi Rhodes also wrote before the eraoption was done: "They just took my love @CodyRhodes back for surgery. Hate being on the waiting end this time. But I know he’s going to feel so much better in time for #DoubleOrNothing"
Dave Meltzer reported last month that Cody would be undergoing arthroscopic knee surgery in Atlanta today. Meltzer wrote that the surgery would keep Cody out of action for two to three months, but he isn't scheduled to wrestle until All Elite Wrestling's Double or Nothing event on May 25.
Cody suffered the injury when teasing throwing a T-shirt into the crowd at ROH's Global Wars tour show in Buffalo on November 9. An MRI revealed that he had two tears in his meniscus, and Cody opted to wait until after his matches at Final Battle and Wrestle Kingdom 13 until having surgery.
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Monday, 4 February 2019

Stem Cell Therapy Breakthrough Could Help Cure Type 1 Diabetes

 22:20     Cure Type 1 Diabetes, Diabetes Stem Cell, Stem Cell diabetes, Stem Cell India, Stem Cell Therapy, Stem Cell Therapy for diabetes, Stem Cell type 1 diabetes     No comments   

Stem Cell Therapy breakthrough could help cure type 1 Diabetes
MOLEKUUL/SCIENCE PHOTO LIBRARY via Getty Images
Scientists have edged one step closer to a major treatment for (and possibly cure for) type 1 diabetes. A UCSF team has claimed it's the first to turn human stem cells into the mature, insulin-producing cells that type 1 patients don't have. The key was to acknowledge reality in the development of islets, or clusters of healthy beta cells (which generate insulin) in the pancreas. They separated partly differentiated pancreatic stem cells into islets, jumpstarting their development and leading to responses to blood sugar that more closely represented mature cells. Even alpha and delta cells grew more effectively, UCSF said.

The technique has only been tested in mice so far, but the results were positive. It took just a "matter of days" for implanted islets to produce insulin as well as the rodents' native cells.

If the research continues to bear fruit, though, it could offer a much more realistic solution for type 1 diabetes. Pancreas transplants can help, but they frequently fail and still require drugs that suppress your immune system. There are tests for safer and more targeted islet implants, but they still tend to require organs from dead donors. This breakthrough could lead to on-demand implants and make it relatively easy to gain (or regain) healthy insulin levels.

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